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The international journal of biochemistry & cell biology, 29(5), 743-751

Developing combinational therapies that address neuronal hyperexcitability as well as oxidative stress may prevent the deleterious cycle of neuroinflammation and oxidative stress that contribute to epileptogenesis

Your body removes waste products through your: Stool Urine Sweat Three of the organs and systems that are involved in detoxification, among others, are the: Liver Interstitium- a network of connective tissue and fluid-filled compartments found throughout your body Immune system These organs and systems form part of the Detoxification circuit in the NeuroEndoMetabolic (NEM) Stress Response System

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Consistent with this view, experimental evidence indicates that intercellular mitochondrial sharing and structural remodeling in granulosa and cumulus cells can enhance energy metabolism and mitigate age-associated functional deterioration, highlighting the functional relevance of organelle interactions beyond individual cells [26]

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