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Description

Expert Rev Proteomics (2021) 18(3):23340

Stability of N -glucuronides Enterohepatic recycling increases the half-life and the residence time for a drug being recycled, thus increasing systemic exposure and a delay in clearance

Itaconate, a metabolite of cis -aconitate that accumulates concurrently with succinate during ischemia, can also function as a competitive inhibitor of succinate dehydrogenase

(Basel) 15, 3014

Some proposed risk factors which might make patients more vulnerable to methimazole-induced hepatotoxicity are summarized in Figure 5

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