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Similarly, the female showed an upregulation of GST expression by up to 6 and 2-folds after 40 and 60 d of wPE exposure, respectively ( Figure 1D )

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Mitochondrial production of ROS also plays a key role in oxidative stress (Madamanchi and Runge, 2007), so one would predict that estrogen may also have an important impact on vascular oxidative stress

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[DOI] [PubMed] [Google Scholar] 52.Vercellotti GM, Khan FB, Nguyen J, Chen C, Bruzzone CM, Bechtel H, et al