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Could G6PD play a role in response to vaccination or in predispositions to autoimmunity

A retrospective cohort studies using the TriNeX database found that GLP-1 RA therapy combined with insulin was associated with a higher risk of diabetic retinopathy (HR, 1.21

PLoS Biol 5(7):e172 Pyle A, Brennan R, Kurzawa-Akanbi M, Yarnall A, Thouin A, Mollenhauer B, Burn D, Chinnery PF, Hudson G (2015) Reduced cerebrospinal fluid mitochondrial DNA is a biomarker for early-stage Parkinsons disease

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For example, it was recently found that that replacement of growth hormone could improve cerebral metabolism, knowledge, memory, and behavior in mild cognitive impairement (70), and that replacement of a natural signaling peptide called Gonadotropin-Releasing Hormone (GnRH) could significantly improve learning and cognition in Down's syndrome patients (71)