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These results identify VEGF as a major mediator of hair follicle growth and cycling and provide the first direct evidence that improved follicle vascularization promotes hair growth and increases hair follicle and hair size

Steroid 5-reductase (5AR) enzyme dictates the cellular availability of dihydrotestosterone to prostatic epithelial cells and consequently modulates its growth

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In contrast, strict selection mediated by low antigen concentrations accelerates affinity gains but increases the risk of population extinction before high-affinity variants can emerge [11]

Promotes collagen, elastin, and connective tissue remodeling

doi: 10.1016/j.immuni.2014.04.007 102 SchmidtHRajTONeillTJMuschaweckhAGiesertFNegraschusAet al