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Description

Cellular deconvolution of bulk transcriptomic data from the peri-infarct cortex showed that cells with molecular signature similar to the so-called disease-associated astrocytes, originally described in the vicinity of -amyloid plaques in a mouse model of AD and in the aged brain 464 , are present also in post-stroke tissue 383

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10.1142/S021797921840009X

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Most notably, ALA upregulates gamma-glutamylcysteine ligase (-GCL), the rate-limiting enzyme required for the synthesis of glutathionethe body's master intracellular antioxidant

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This study aimed to evaluate the toxic effect of the simultaneous exposure of the undifferentiated human SH-SY5Y neuroblastoma cell line to MDMA and tramadol or MDMA and tapentadol, focusing on serotonin toxicity

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Human clinical trial data remains the weak link across every application

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doi: 10.1007/s10495-016-1336-0 139 YangQ.LiaoM.WangW.ZhangM.ChenQ.GuoJ.et al

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