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Finally, the biggest risk is for people who have pernicious anemia, a rare condition in which a person is unable to absorb any B12 through their stomach or intestines people with this condition are the ones who actually need B12 injections

Its relevance to neuropathy comes through serotonin synthesis promotion and neuroprotective gene expression modulation

Bertiaux-VandaleNYoumbaSBBelmonteLLecleireSAntoniettiMGourcerolGet al

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The 10-day window is intended to deliver a concentrated signaling effect to the cells involved in circadian regulation and renewal before the long rest allows those adaptations to consolidate

The study also found that PRP had few adverse effects (such as short-term pain increase), but these effects were transient