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These results, which suggest that dihexa is very hydrophobic (logP) and are in agreement with the outcome of QSAR modeling estimates generated by ADMET Predictor that calculated an octanohwater partition coefficient of 177.8 for dihexa (Table 10)

One other important note to make here: Only 57.3% of CagriSema patients reached the highest dose by 68 weeks, compared to 82.5% for Cagrilintide and 70.2% for Semaglutide monotherapy