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Recognising the true causes is the first step towards effective solutions rather than attributing them to serious medical conditions like liver disease

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[DOI] [PMC free article] [PubMed] [Google Scholar] 10.Cross C.E., Halliwell B., Borish E.T., Pryor W.A., Ames B.N., Saul R.L., McCord J.M., Harman D

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The key histological abnormalities of AD include necrosis and apoptosis of VSMCs, fracture of elastic fibers, and degradation of extracellular matrix (ECM) (73).The thrombi formed within the false lumen indicates the presence of continued inflammation under the condition of atherosclerosis and chronic inflammation, and the higher risk of rupture in patients with inflammatory diseases demonstrates the importance of inflammation in AD (74)

ACT-based immunotherapies can elicit significant tumor regression in animal models and also up to 70% of metastatic melanoma patients