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2020, Feb, 3;10(1):52 Almeida FM, Battochio AS, Napoli JP, Alves KA, Balbin GS, Oliveira-Junior M, et al

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In silico gene expression analysis reveals glycolysis and acetate anaplerosis in IDH1 wild-type glioma and lactate and glutamate anaplerosis in IDH1-mutated glioma

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On the one hand, cancer metabolism-related signals or metabolites affect the activation and function of microenvironmental antitumor immune cells (T cells and NK cells) in the TME, and on the other hand, cancer-associated stromal cells, such as CAFs, and immunosuppressive cells (M2 macrophages and MDSCs) reshape the local metabolic environment and oncogenic pathways, further promoting malignant tumor progression

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doi: 10.1089/ars.2012.5143 197 YasuhikoH

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However, the research in this area is still inconclusive

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Learn how Glutathione works to protect cells, fight toxins, and support immunity

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