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SAB, by activating the Nrf2 signaling pathway, shifted microglia from the M1 phenotype to the M2 phenotype, reducing neuronal damage (Zhang et al., 2017)

Myo-Inositol serves as a well-established glial marker due to its preferential uptake by astrocytes and its role in maintaining cerebral osmotic homeostasis, while also being associated with microglial activity (Solomonia et al., 2013)