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There is no universal recommendation, and the choice should ideally be guided by clinical assessment and, where appropriate, laboratory testing

Given the strength of the observed relationship between the optimum temperature and the most frequently experienced temperature in the current climate as well as the reduction in heat deaths despite warming over time, any projection that does not allow the minimum mortality temperature to adjust with local warming cannot provide credible projections of changes in deaths due to non-optimal temperature

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P., & Guilford, F

Animals were randomly divided into five groups: control, BPC10, BPC20, BPC40 and morphine