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Their core mechanism lies in being bio-reductively activated in specific low-oxygen regions, actively releasing or generating large amounts of ROS for precise killing

[DOI] [PubMed] [Google Scholar] 210.Park S., Kang S., Yoo S., Park Y., Seo K

Controlled reperfusion provides complete neurologic recovery following 30 min of warm ischaemiathe importance of perfusion pressure

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Cytosolic CK19 bound to AR domain of Notch2 intracellular domain (NICD2) to stabilize NICD2 protein level and trigger Notch signaling, which contributed to hepatocyte transformation to ICC cells