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[DOI] [PMC free article] [PubMed] [Google Scholar] 143.Gamulin O., Oroz K., Coric L., Krajacic M., Skrabic M., Dretar V., Strbe S., Talapko J., Juzbasic M., Krezic I., et al

Bioavailability is still lower than injection, but for patients avoiding needles it is worth discussing with a physician

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No adverse effects were observed on reproductive parameters when male dogs received 10 consecutive daily treatments of 15 mg/kg/day at 3 intervals (90, 45 and 14 days) prior to breeding or when female dogs received 10 consecutive daily treatments of 15 mg/kg/day at 4 intervals: between 30 and 0 days prior to breeding, early pregnancy (between 10th & 30th days), late pregnancy (between 40th & 60th days), and during lactation (the first 28 days)