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Advancements in ALS outcomes, ALS clinical trials, and drug discovery have the potential to speed drug development for this fatal disease

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In hereditary or acquired metabolic defects, an initial intravenous bolus of 50 mg/kg may be administered over two to three minutes, followed by maintenance doses of 50 mg/kg every six hours or continuous infusion to achieve a total daily exposure of up to 300 mg/kg in critical illness

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Pueden producirse efectos anticatablicos al mejorar el equilibrio de nitrgeno, ya sea mediante una mayor sntesis de protenas o una reduccin de la degradacin de las protenas

& du Plessis, S