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Posterior subcapsular cataracts are formed after radiation with x-rays and long-term corticosteroid therapy

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One study analyzed clinical samples of liver transplantation provided by the Department of Liver Transplantation of Renji Hospital and found that the ubiquitination ligase E3 Huwe1/Mule was significantly down-regulated at the protein and mRNA levels after liver transplantation, suggesting the important effect of Huwe1/Mule on liver transplantation[29]