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UVA1 radiation triggers two different final apoptotic pathways

The active metabolite of vitamin D, 1,25-dihydroxyvitamin D3 (1,25D), must form a VDR-RXR heterodimer with RXR after binding to vitamin D receptor (VDR), so as to effectively recognize and bind to VDREs in the promoter region of the target gene and initiate transcriptional regulation

Lee J, Takeuchi H, Fervaha G, Sin GL, Foussias G, Agid O, et al

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During the procedure, you may feel some pain from the injections, but it is generally a light pain