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These developments include (but perhaps are not limited to): (i) the availability of the first genome-wide siRNA sets, at least theoretically permitting the downregulation of each mRNA encoded by the human or murine genome

These chemical modifications are often tailored for RNA-based therapies to enhance stability, preserve biological function, and minimize immunogenicity, which is crucial for avoiding unwanted immune responses in cancer patients

"Fermentation in cyanobacteria1"

108(9), p

Wierda W, OBrien S, Albitar M, Lerner S, Plunkett W, Giles F, Andreeff M , Cortes J, Faderl S, Thomas D, Koller C, Kantarjian H, Keating M

Reduced vitamin E levels have been reported in studies on individuals affected by type 1 diabetes, and supplementation of vitamin E has been used to reduce oxidative stress [28]