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Ann Rheum Dis 76:18971905

Nerve compression occurs when excessive pressure is applied to a nerve by surrounding tissues, such as muscles, tendons, or bone growths

Gong J, Hu X, Zhang J, Du Y, Huang R, Teng Y, Tan W, Shen L (2021) Phase Ia study of CBP-1008, a bi-specific ligand drug conjugate targeting FR and TRPV6, in patients with advanced solid tumors

Formulated to work with the body's own pulsatile signaling patterns

Liver (Hepatic Glucose and Lipid Metabolism): By suppressing glucagon and increasing insulin, GLP-1 RAs reduce hepatic glucose production (gluconeogenesis) (Zheng et al., 2024)

We adjust the dose based on these parameters, and include ancillaries such as aromatase inhibitors where necessary and as agreed with the patient