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153 Thus, whether these observations constitute examples of bona fide on-target resistance or rather reflect the critical role of mitochondria (and in particular of the PTPC) in CDDP-elicited cell death, hence constituting examples of post-target resistance, remains an open conundrum

IGFBP7 is a member of the SASP factor family, and it can suppress the signaling process through the IGF-1 receptor (IGFIR)

For example, if the glutaredoxin sulfur atom in Grx(SSR) species was accessible for a productive reaction with GSH, one would not expect to trap such species by monothiol glutaredoxin mutants 83,84,85

Behboudi F, Zeinolabedin TS, Mohammad ZK, Seyed AMMS, Ali MB

Recent studies have found that SLC39A14 promotes hepatocyte ferroptosis through the delivery of NTBI

Ilamathi M, Santhosh S, Sivaramakrishnan V