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Wipe top of medication bottle with alcohol prep Use separate needle for drawing medication from bottle so as not to contaminate medication- to do this if you are using a syringe and needle combo, unscrew the needle on the syringe, and screw the syringe into the needle that is already in the rubber stopper of the medication (One that you have already placed there for this purpose) - once the syringe has the proper dosage of medication in it, unscrew the needle that is In the medication bottle and re-screw the needle you removed before filling the syringe back onto the syringe