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Binding of HE to pancreatic lipase reduces the structural stability of the enzyme

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and the FI group up-regulated 28 differential metabolites and down-regulated 32 differential metabolites relative to the GSH group

However, it is a poorer precursor as it requires methyl ester modification for transport into the cell 37,38

Depriving tumours of extracellular glutathione or inhibiting its breakdown is potentially a viable therapeutic strategy for cancer patients, the authors state