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These processes include DNA methylation, histone modifications, and the action of non-coding RNAs

Kalaras MD, Richie JP, Calcagnotto A, Beelman RB

Natural compounds Baicalin is a primary active substance from the Scutellaria root and attenuates ER stress-related apoptosis in vivo mediated by CHOP/eNOS signaling pathway (210)

D., Kim, C

Exendin-4 Enhances Proliferation of Senescent Osteoblasts Through Activation of the IGF-1/IGF-1R Signaling Pathway

These examples clearly indicate that the activation of STAT3 signaling is able to trigger cellular senescence, probably in co-operation with NF-B and SMAD3 signaling