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Among them, specifically targeting the downstream mediators of c-Met involved in tumor progression is a promising method, including the Grb2 SH2 domain, Src, MAPK, STAT3, Shp2 (Liu et al., 2018), and Fak (Jo et al., 2015)

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This selective signaling behavior allows researchers to examine how peptide fragments can retain specific biological functions while avoiding broader receptor activation

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Epitalon (sometimes spelled Epithalon) is another synthetic tetrapeptide and often described as Ala-Glu-Asp-Gly (AEDG)

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