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This proposal, which implies that limiting or inhibiting the formation of free radicals could reduce the rate of aging and prevent age-associated diseases, is receiving growing acceptance as a possible explanation of the aging theory

Arch Fam Med 3(2):193-5

K.FalsafiT

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Francis et al

299 In addition, UHRF1 can recruit KDM4C and further regulate the transcription of CDC6 through the demethylation of H3K9 by KDM4C, which is crucial for cell resistance