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This strategy enabled us to determine high-resolution structures of hTauT in multiple conformational states: the apo state in the inward-occluded conformation and the inward-open conformation (2.8 and 3.3 , respectively), the taurine-bound state in the inward-occluded conformation at 2.9 , the -alanine-bound state in the inward-occluded conformation at 2.7 , and the P4S-bound state in the inward-occluded conformation and inward-open conformation (2.8 and 3.2 , respectively) (Supplementary Figs

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References For Further Reading (1) V N Anisimov and V K Khavinson (2010) Peptide bioregulation of aging: results and prospects Biogerontology, 2010 Apr, Volume 11 (Issue 2), Pages 139-49

Pregnancy If you are pregnant or breastfeeding, you may not be suitable for B12 injections, but it is still safe for you and your baby if you take a limited dose of B12 orally