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Because they are highly effective solvents

References Brunton SA, Mosenzon O, Wright EE Jr

10.1016/j.amsu.2018.08.012 94 RoselliH

The conditions, such as a 75 mM sodium phosphate buffer (pH 3.0) with 1.7 mM 1-octanesulfonic acid, 25 M EDTA, 10% methanol, and a flow rate of 1 mL/min, are optimized for precision and sensitivity, ensuring accurate neurotransmitter profiling at a column temperature of 25C

This process is commonly employed in research laboratories when working with peptide reference standards, proteins, and other biomolecules that are supplied in lyophilised form for stability during storage and transport

The gut and immune system also depend on microbes