oxidised glutathione solubility quality raw materials for production of classical and novel therapies Toxicity of Glutathione-Binding Metals: A

In other ASD models, such as 15q dup mice [34], Oprm1 -KO mice [42], Oxtr -KO mice [33], and C58/J mice [38], oxytocin selectively improved social deficits, without influencing other ASD symptoms

PER has also been demonstrated to have antiapoptotic, anti-inflammatory, and antioxidant properties (Varin et al

Geng B, Qin H, Zheng F, Shen W, Li P, Wu K, et al

L., Yu, T

[17] Regulation of the nitric oxide cycle, which is critical for life but can be problematic if unregulated [18] It is used in metabolic and biochemical reactions such as DNA synthesis and repair, protein synthesis, prostaglandin synthesis, amino acid transport, and enzyme activation

Summing up, it is plausible that vitamin B12 deficiency may result in a decrease in SAM concentration, which will translate into inhibition of CBS activity and, as a result, may lead to a reduction in glutathione synthesis, which will affect cell redox reactions