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10.1111/fcp.12543 149 MaN.LiuH

Autophagy is a cellular process responsible for degrading and recycling cellular components, but this process is often impaired in neurodegenerative disorders, leading to failure in clearance of toxic protein aggregates [7]

A similar increase in Ser38 phosphorylation is observed under hypoxic conditions in yeast SOD1 (Thr39 in human SOD1), and is proposed to explain why cellular antioxidant capacity is diminished under hypoxic conditions